Intraoperative Conversion During Video-assisted Thoracoscopy Resection for Lung Cancer Does Not Alter Survival
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 843
- 试验地点
- 1
- 主要终点
- Overall survival during the follow-up period after surgery
研究概览
简要总结
Anatomical resection with systematic lymph-node dissection is currently the standard of care for the treatment of early stage non-small cell lung cancer. The use of minimally invasive approaches has increased greatly over the last two decades [either video-assisted thoracoscopic surgery (VATS) or robotic-assisted thoracoscopic surgery (RATS)], as they provide the patient with better outcomes than open thoracotomy. Minimally invasive VATS lobectomy for a standard case is generally a straightforward procedure for a well-trained surgical team, although concomitant preoperative pathologies or intraoperative findings/adverse events may result in technical difficulties, leading to intraoperative conversion, commonly by thoracotomy.
The investigators aimed to assess long-term outcomes in a consecutive cohort of patients treated by anatomical pulmonary resection either using VATS, VATS requiring intraoperative conversion to thoracotomy, or upfront open thoracotomy for lung-cancer surgery.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —(Adult, Older Adult)
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All consecutive patients treated by anatomical lobar pulmonary resection (lobectomy, bilobectomy) or anatomical sublobar pulmonary resection (segmentectomy) for non-small cell lung cancer (NSCLC), either by VATS (eventually with intraoperative conversion) or upfront thoracotomy.
排除标准
- •patients with non-anatomical pulmonary resection (wedge resection)
- •patients with a histology other than NSCLC (benign or metastatic from another primitive cancer), stage IV NSCLC disease,
- •patients with multiple primary NSCLC (synchronous or metachronous)
- •patients with incomplete resection (R+)
- •patient for whom a VATS approach was never considered
结局指标
主要结局
Overall survival during the follow-up period after surgery
时间窗: from day of surgery up to 7 years
次要结局
未报告次要终点
