A prospective, observational study to examine the effects of ageing on the clinical outcomes of people living with HIV in England and Ireland. - POPPY Pharmacokinetic and clinical observations in people over fifty

Imperial College, Research Governance Manager0 个研究点目标入组 2,000 人开始时间: 2012年8月14日最近更新: 2012年10月16日

适应症

试验速览

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•Older HIV-positive cohort (n=1000):
•documented HIV infection
•age >50 years at study entry
•self defined white or black African ethnicity
•likely route of HIV acquisition via sexual exposure
•able to comprehend study patient information leaflet
•Younger HIV-positive cohort (n=500):
•documented HIV infection
•age <50 at study entry*
•self defined white or black African ethnicity
•likely route of HIV acquisition via sexual exposure
•able to comprehend study patient information leaflet
•* this group will comprise of at least 150 subjects in each of the following age groups: 20-29, 30-39, 40-49 years. Recruitment will be monitored by the Study Monitoring Team
•HIV-negative cohort (n=500):
•documented negative HIV test at screening
•age >50 years at study entry
•self defined white or black African ethnicity
•registered with a General Practitioner
•The control groups will be frequency matched to the cases on gender, ethnicity, mode of HIV acquisition and clinic location.
•Are the trial subjects under 18? no
•Number of subjects for this age range: 0
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range 1800
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range 200

•in the opinion of the investigator, those unable or unwilling to comply with the requirements of the study
•life expectancy less than 6 months

发起方

Imperial College, Research Governance Manager