Efficacy and Safety of Cream Containing Sericin and Turmeric in Psoriasis Patients
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 主要终点
- Psoriasis Area and Severity Index
研究概览
简要总结
Psoriasis lesion is divided into two parts. Half of the lesion will apply cream containing sericin and turmeric and another will apply steroid cream (control). The samples will be apply two times a day for 8 weeks. Psoriasis area and severity index, physician global assessment, body surface area of lesion, dermatology life quality index, Itching score, adverse reaction are evaluated before, after using the samples for 4 and 8 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Age over 18 years
- •Patients with body surface area of psoriasis lesion less than 10, have psoriasis area and severity index less than 10 , and no lesion at face, hands,feet, and genital area
- •No topical application on psoriasis lesion at least 2 weeks
- •Willing to attend the study
排除标准
- •Uncontrolled diseases
- •Allergic to sericin turmeric and steroid
- •Other skin diseases
- •Pregnancy and lactation
研究组 & 干预措施
Sericin extract and turmeric extract cream
Apply the sample 2 times a day for 8 weeks
干预措施: Sericin extract and turmeric extract cream (Drug)
Triamcinolone acetonide 1% cream
Apply the sample 2 times a day for 8 weeks
干预措施: Triamcinolone acetonide 1% Cream (Drug)
结局指标
主要结局
Psoriasis Area and Severity Index
时间窗: 8 weeks
Physician will evaluate the psoriasis lesion using Psoriasis Area and Severity Index. The score is graded 0 to 72 (low score means less severity and high score means high severity).
次要结局
- Physician Global Assessment(8 weeks)
- Itching score(8 weeks)
- Body surface area of lesion(8 weeks)
- Dermatology Life Quality Index(8 weeks)
研究者
Pornanong Aramwit, Pharm.D., Ph.D
Professor
Chulalongkorn University