Randomized Controlled Research of the Application of Triple Antibiotic Paste in Primary Teeth With
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Evidence of lesion healing confirmed by cone beam computed tomography and X-rays
研究概览
简要总结
The triple antibiotic paste is widely used in young permanent teeth and permanent teeth root canal therapy with excellent antiantimicrobial effect.We hypothesize that its application in the treatment of periapical periodontitis of deciduous teeth is superior to other drugs currently in use as creosote.
详细描述
We design to collect a group of patients presenting primary teeth with periapical periodontitis in certain criterion. We will divide the patients into two groups randomly.One group will get treated with triple antibiotic paste while the other with creosote.We want to evaluate the short-term and long-term effects of the two groups to get a conclusion of the clinical value of triple antibiotic paste.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 3 Years 至 8 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •clinical diagnosis of periapical periodontitis
- •must be primary teeth
- •must be 3~8 years old
- •the permanent tooth germ is complete and didnot be involved
排除标准
- •blood disease
- •residual root that is advised to extract
- •serious periodontitis
- •allergy to the triple antibiotic paste
研究组 & 干预措施
creosote
Creosote ，once，three weeks Triple Antibiotic Paste ，none
干预措施: creosote (Drug)
Triple Antibiotic Paste
Triple Antibiotic Paste,once,three weeks creosote,none
干预措施: Metronidazole-Ciprofloxacin gatifloxacin-Clindamycin paste (Drug)
结局指标
主要结局
Evidence of lesion healing confirmed by cone beam computed tomography and X-rays
时间窗: 1 year
次要结局
未报告次要终点
研究者
Lin Jiacheng
Research Associate
Sun Yat-sen University