The Development of an Artificial Intelligence Platform for Screening and Referral of Cognitive Dysfunction
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 1,539
- 试验地点
- 1
- 主要终点
- Area under the curve
研究概览
简要总结
There is association between eye movement disorder and cognitive dysfunction. Therefore, utilizing eye movement and screening for cognitive dysfunction is feasible. In the present study, the investigators will develop an artificial intelligence platform to screening for cognitive dysfunction by inspecting the function of eye movement. Futher more, based on the screening results, the platform will offer referral suggestions.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Crossover
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 45 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •①Subjects who are diagnosed as mild cognitive decline, Alzheimer's disease, Vascular dementia, Lewy body dementia, Frontotemporal dementia, other dementia and normal by neurologist.
- •②Subjects who can cooperate with the inspection.
- •③Subjects who agree to participate in the study and sign the consent form
排除标准
- •①Subjects who cannot do the inspection.
- •②Subjects who suffer from diseases that compromise the inspection.
研究组 & 干预措施
Vascular dementia
Subjects who are diagnosed as vascular dementia(VD) according to neurologists.
Lewy body dementia
Subjects who are diagnosed as Lewy body demenita (DLB) according to neurologists.
Frontotemporal dementia
Subjects who are diagnosed as Frontotemporal demenita (FD) according to neurologists.
Other dementia
Subjects who are diagnosed as dementia but are not as AD, VD, DLB OR FD.
Normal
Subjects over 45 years old without cognitive dysfunction
Mild cognitive decline
Subjects who are diagnosed as mild cognitive decline(MCI) according to neurologists.
Alzheimer's disease
Subjects who are diagnosed as Alzheimer's disease(AD) according to neurologists.
结局指标
主要结局
Area under the curve
时间窗: up to 1 month
AUC values for predicting whether subject has cognitive impairment or not
次要结局
- Accuracy, true positive rate, and true negetive rate(up to 1 month)
研究者
Haotian Lin
Professor
Sun Yat-sen University