临床试验/NCT00649909

NCT00649909已完成不适用

Effect of Glucose Control on the Response to Aspirin in Type 2 Diabetic Patients

Hadassah Medical Organization1 个研究点分布在 1 个国家目标入组 18 人开始时间: 2008年11月最近更新: 2017年8月10日

适应症

试验速览

阶段: 不适用
状态: 已完成
发起方: Hadassah Medical Organization
入组人数: 18
试验地点: 1
主要终点: The outcome measure is the laboratory Aspirin Resistance.

研究概览研究设计入排标准结局指标研究者研究点记录与标识符相似试验

研究概览

简要总结

The efficacy of low dose aspirin appears to be substantially lower in diabetic patients, compared to patients without diabetes.

We will perform an observational study where we follow up patients with uncontrolled type 2 Diabetes Mellitus and low response to aspirin (Aspirin Resistance), during a period of 6 months in the diabetic clinic. Our hypothesis is that glucose control will improve the response to aspirin in those patients.

研究设计

研究类型: Observational
观察模型: Cohort
时间视角: Prospective

入排标准

性别: All
接受健康志愿者: 否

入选标准

未提供

排除标准

•Acute ischemic stroke, acute coronary syndrome, (myocardial infarction or unstable angina pectoris), or revascularization by PCI or by-pass surgery within the last 6 months.
•Acute kidney disease or chronic kidney disease with creatinine clearance <
•Acute liver disease or chronic liver disease with severe liver impairment.
•Need for treatment with anticoagulants, clopidogrel, NSAID's, or thiazolidinediones.
•Thrombocytopenia (platelet count <150 x 109/L)

结局指标

主要结局

The outcome measure is the laboratory Aspirin Resistance.

时间窗: 3 and 6 months.

次要结局

To determine the incidence of laboratory aspirin resistance in type 2 DM in stable out-patients in the diabetic clinic, and possibly related factors.(On screening visit.)

研究者

发起方

Hadassah Medical Organization

申办方类型

Other

责任方

Principal Investigator

主要研究者

David Varon

Director of coagulation unit

Hadassah Medical Organization

研究点 (1)

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