NCT03692676已完成不适用
Characteristics of Patients Initiating Spiriva Respimat in Asthma in the UK: a Cross-sectional Study Based on the Clinical Practice Research Datalink
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 116,133
- 试验地点
- 1
- 主要终点
- Number of Participants With Cardiac Arrhythmias
研究概览
简要总结
This study is a cross-sectional, non-interventional study based on existing data (NISed).
详细描述
The UK CPRD data will be used to assess the characteristics of asthma patients who were prescribed ICS/LABA FDC before the index date and who initiated Spiriva Respimat, or received a higher dose of ICS/LABA FDC, or initiated LTRA, or switched to a new ICS/LABA FDC in the UK during the study period (September 2014-December 2017) enabling to assess potential channeling of prescribing to different patient populations.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Aged 18 years and above at the index date
- •At least 12 months of continuous registration prior to the index date in a practice contributing up to standard (UTS) data to the Clinical Practice Research Database (CPRD)
- •Had a diagnosis of asthma before the index date
- •Being treated with Inhaled corticosteroids/Long-acting beta agonists (ICS LABA FDC) before the index date (at least one prescription within 3 months before the index date)
- •Patients who were new users of Spiriva Respimat, or LTRA, or patients who were prescribed a higher dose of ICS/LABA FDC, or patients who switched to a new ICS/LABA FDC from the previous ICS/LABA FDC
排除标准
- •Patients who were prescribed other Long-acting muscarinic antagonists (LAMA) any time before or on the index date
- •In the primary analysis, patients who were diagnosed with COPD before or on the index date will be excluded from the study. In a sensitivity analysis, patients who had both asthma and COPD diagnoses will be included in the study
结局指标
主要结局
Number of Participants With Cardiac Arrhythmias
时间窗: On the index date or in the year prior to the index date
The number of participants who had Cardiac arrhythmias on the index date or in the year prior to the index date.
次要结局
- Number of Participants With Cardiac Failure(On the index date or in the year prior to the index date)
研究者
研究点 (1)
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