Increased FIO2 Influences SvO2 Interpretation and Accuracy of Fick-based Cardiac Output Assessment in Cardiac Surgery Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 50
- 主要终点
- The Hemoglobin Values in Different FIO2 Groups during Cardiac Surgeries
研究概览
简要总结
In this study, the investigators sought to clarify the influence of FIO2 levels on the variables in the Fick equation and then assessed the influence of each variable on the accuracy of Fick-CO measurements in patients undergoing cardiac surgery.
详细描述
Patients who are aged ≥20 years, are undergoing planned elective cardiac surgery, and provided signed informed consent are included in the present study. Any patients with an intra-cardiac shunt are excluded.
The patients are randomly assigned to 2 groups: FIO2 <0.7 or FIO2 >0.85. And during the surgery, the oximeter values are kept ≥98%. Intra-operatively, FIO2, PaO2, SaO2, SvO2, PvO2, Hb, blood pH values, body temperature and TD-CO are recorded.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •undergoing planned elective cardiac surgery
- •agree to sign informed consent
排除标准
- •intra-cardiac shunt
结局指标
主要结局
The Hemoglobin Values in Different FIO2 Groups during Cardiac Surgeries
时间窗: under general anesthesia but before surgical incision
The patients were divided into two FIO2 groups (FIO2 \>0.85 or \<0.7) during the surgery. We will collect hemoglobin data in each patient.
The Oxygen Consumption in Different FIO2 Groups during Cardiac Surgeries
时间窗: under general anesthesia but before surgical incision
The patients were divided into two FIO2 groups (FIO2 \>0.85 or \<0.7) during the surgery. We will use the LaFarge equation to calculate oxygen consumption (ml/min/m\^2) in each patient.
The Blood PH Values in Different FIO2 Groups during Cardiac Surgeries
时间窗: under general anesthesia but before surgical incision
The patients were divided into two FIO2 groups (FIO2 \>0.85 or \<0.7) during the surgery. We will calculate oxygen consumption in each patient.
The Body Temperatures in Different FIO2 Groups during Cardiac Surgeries
时间窗: under general anesthesia but before surgical incision
The patients were divided into two FIO2 groups (FIO2 \>0.85 or \<0.7) during the surgery. We will calculate oxygen consumption in each patient.
The SaO2 in Different FIO2 Groups during Cardiac Surgeries
时间窗: under general anesthesia but before surgical incision
The patients were divided into two FIO2 groups (FIO2 \>0.85 or \<0.7) during the surgery. We will calculate oxygen consumption in each patient.
The SvO2 in Different FIO2 Groups during Cardiac Surgeries
时间窗: under general anesthesia but before surgical incision
The patients were divided into two FIO2 groups (FIO2 \>0.85 or \<0.7) during the surgery. We will calculate oxygen consumption in each patient.
The PaO2 in Different FIO2 Groups during Cardiac Surgeries
时间窗: under general anesthesia but before surgical incision
The patients were divided into two FIO2 groups (FIO2 \>0.85 or \<0.7) during the surgery. We will calculate oxygen consumption in each patient.
The PvO2 in Different FIO2 Groups during Cardiac Surgeries
时间窗: under general anesthesia but before surgical incision
The patients were divided into two FIO2 groups (FIO2 \>0.85 or \<0.7) during the surgery. We will calculate oxygen consumption in each patient.
次要结局
- The Precision of Fick-based Cardiac Output in Different FIO2 Groups during Cardiac Surgeries(under general anesthesia but before surgical incision)