Survey of Cannabis Use in Patients With Chronic Inflammatory Arthritis
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 501
- 试验地点
- 1
- 主要终点
- prevalence of cannabis use in patients with chronic inflammatory rheumatic conditions
研究概览
简要总结
Patients with inflammatory rheumatism very often have residual pain that is not easily relieved by conventional treatments. They can then use non-drug methods, such as physiotherapy, hypnosis or even cannabis.
The aim of this study is to assess the percentage of patients who use cannabis to better relieve their pain or anxiety in chronic inflammatory rheumatism.
详细描述
Thanks to a better understanding of the pathophysiological mechanisms of inflammatory rheumatism, rheumatology has known for several decades a growth in its therapeutic arsenal (csDMARDs, bDMARDs, tDMARDs). rheumatism control has thus been optimized.
however, patients very often keep pain, anxiety, residual fatigue, poorly controlled by our conventional therapies. patients then turn to non-drug therapies, among which the use of cannabis.
endocannabinoids have an analgesic and anti-inflammatory action recognized in pre-clinical trials. however, investigators currently lack the data to authorize its use in clinical rheumatology.
the aim of this study is to determine the prevalence of cannabis users in patients with rheumatoid arthritis, ankylosing spondyloarthritis or psoriatic arthritis in our unit. as a second intention, investigators will refine the consumption characteristics. Investigators will also look for possible risk factors for consumption (sensitivity to pain, catastrophism, standard of living, anxiety, depression, rheumatic activity and quality of life).
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Other
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Rheumatoid Arthritis (ACR 2010 Criteria)
- •Ankylosing Spondylitis (New york or ASAS criteria)
- •Psoriatic Arthritis (CASPAR criteria)
排除标准
- •Patient unable to complete questionnaires or unable to express informed consent
- •Guardianship, trusteeship, deprivation of liberties, safeguard of justice
结局指标
主要结局
prevalence of cannabis use in patients with chronic inflammatory rheumatic conditions
时间窗: Day 0
Patients will answer the following question: Are you currently using cannabis - Yes or No
次要结局
- Assessing the association between cannabis use and disease activity of spondylitis ankylosing(Day 0)
- Percentage of patients with problematic cannabis use(Day 0)
- Assessing the association between cannabis use and functional disability(Day 0)
- Assessing the association between cannabis use and Anxiety/Depression(Day 0)
- Assessing the association between cannabis use and disease activity of rheumatoid arthritis / psoriatic arthritis(Day 0)
- Assessing the association between cannabis use and social vulnerability(Day 0)
- Assessing the association between cannabis use and pain catastrophism(Day 0)