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临床试验/NCT00723242
NCT00723242已完成不适用

The Role of Dendritic Cells in Hepatitis C Infection

University College, London2 个研究点 分布在 1 个国家开始时间: 2002年4月最近更新:
适应症
相关药物

试验速览

阶段
不适用
状态
已完成
试验地点
2
主要终点
Basic science research (immunology of hepatitis C)in hepatitis c patients receiving established, standard antiviral treatment (pegylated Interferon+Ribavirin)

研究概览

简要总结

The role of the dendritic cells, the most potent antigen presenting cells, in the establishment of chronic hepatitis C is not established. The study aims to define whether the dendritic cells are affected by the hepatitis C virus and whether that bears an impact on the antiviral immune response they generate. The hypothesis is explored by investigating a group of patients prior to and after the initiation of standard treatment for hepatitis C with pegylated Interferon and Ribavirin.

研究设计

研究类型
Interventional
主要目的
Basic Science

入排标准

年龄范围
18 Years 至 70 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • anti-HCV positive
  • HCV RNA positive

排除标准

  • contraindications for antiviral treatment
  • concurrent chronic viral infections

结局指标

主要结局

Basic science research (immunology of hepatitis C)in hepatitis c patients receiving established, standard antiviral treatment (pegylated Interferon+Ribavirin)

次要结局

未报告次要终点

研究者

申办方类型
Other

研究点 (2)

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The Role of Dendritic Cells in Hepatitis C Infection | 临床试验