NL-OMON37991已完成不适用
Effect of renal sympathetic denervation on renal and overall sympathetic output in patients with therapy resistant hypertension - Effect of renal sympathetic denervation on sympathetic nervous activity
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Observational
入排标准
- 年龄范围
- 18 至 99（—）
入选标准
- •Patients aged 40-70 years receiving RSD for therapy resistant hypertension, defined as daytime ABPM*150/100 mmHg despite the use of 3 or more anti-hypertensive drugs including or with intolerance to a diuretic.;No evidence of secondary hypertension (renal artery stenosis, pheochromocytoma, primary aldosteronism and hyper- or hypothyroidism have to be excluded prior to the intervention). ;Normal renal anatomy, single renal artery bilaterally.;Able to provide informed consent. ;Willingness to participate.
排除标准
- •Renal insufficiency (eGFR<45 ml/min) or proteinuria>1 gram/24 hrs.;Pacemaker or ICD device;Atrial fibrillation;Diabetes Mellitus type 1;Unstable weight 3 months prior to inclusion;Pregnancy ;Treatment of DM type 2 with insulin, PPARγ-agonists or SU-dervatives (for clamp experiment only)
研究者
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