Clinical Efficacy of Combined Application of Diode Laser and Different Remineralizing Agents on Combined Application of Diode Laser and Different Remineralizing Agents on White Spot Lesions
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 45
- 试验地点
- 1
- 主要终点
- Spectrophotometric color assessment:
研究概览
简要总结
Dental caries is a very common condition, and although it has become less common, it still represents a serious public health risk. Caries symptoms range from the earliest molecular alterations in the tooth's apatite crystals to an apparent white spot lesion (WSL) or eventual cavitation. The white spot lesion looks chalky because minerals are being lost from both the surface and the underside of the enamel. A relatively simple and noninvasive caries preventive regimen in treating white spot lesions with low-level laser irradiation, either alone or with topical fluoride treatment. This treatment results in reduced enamel solubility and dissolution.
详细描述
The study was reviewed and approved by the "Ethical research committee "of the Faculty of Dental Medicine for Girls; at Al-Azhar University, Cairo, Egypt. This study was conducted on 90 teeth with white spot lesions (WSLs) detected clinically on the buccal surface of teeth. The patients with WSLs were selected randomly from the operative dentistry clinic at the Faculty of Dentistry, Girl's Branch, Al-Azhar University
After examination, the teeth will be assigned into six groups of 15 teeth with white spot lesions each according to the remineralizing material used:
- The first group (A1B1): The teeth with WSL will be treated with nano-hydroxyapatite +fluoride with laser application.
- The second group (A1B2): The contralateral teeth will be treated with nano-hydroxyapatite +fluoride without laser application.
- The third group (A2B1): The teeth with WSL will be treated with nano-hydroxyapatite + xylitol with laser application.
- The fourth group (A2B2): The contralateral teeth will be treated with nano hydroxyapatite+ xylitol without laser application.
- The fifth group (A3B1): The teeth with WSL will be treated with 5% sodium fluoride varnish with laser application.
- The sixth group (A3B2): The contralateral teeth will be treated with 5% sodium fluoride without laser application.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Single (Investigator)
盲法说明
To avoid bias and for proper randomization, the study will be done per patient using tossing a coin to assign the tooth to be either treated with Nano hydroxyapatite with fluoride or Nano hydroxyapatite with xylitol or sodium fluoride.
入排标准
- 年龄范围
- 15 Years 至 40 Years（Child, Adult）
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •The patients should be 13-40 years old.
- •Patients should have good oral hygiene.
- •The patients with good general health and no systemic disease.
排除标准
- •- Presence of enamel hypoplasia or dental fluorosis.
- •Presence of carious cavity.
- •Patients who have a significant medical history,
- •Patients who have evidence of reduced salivary flow or significant tooth wear.
结局指标
主要结局
Spectrophotometric color assessment:
时间窗: from base line (application of materials) to one month
The Vita Easy shade spectrophotometer (Vita Zahnfabrik, Bad Säckingen, Germany) was employed for the color assessment WSLs
次要结局
- surface area measurement(from base line (application of materials) to one month)
研究者
Amani abdullah Omar bin shahna
operative clinic
Al-Azhar University