ACTRN12610000836033已完成4 期
Metformin for the management of insulin resistance in overweight women at midlife.
适应症
试验速览
- 阶段
- 4 期
- 状态
- 已完成
- 入组人数
- 124
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomised controlled trial
- 主要目的
- Prevention
- 盲法
- Blinded (masking used)
入排标准
- 年龄范围
- 35 Years 至 65 Years（—）
- 性别
- Female
入选标准
- •Women:1. who are aged between 35-65 years. 2. who have a BMI >30kg/m2 and <40kg/m2 and/or a waist circumference > 88cm. 3.who have provided informed consent.
排除标准
- •1. Women with any of the following: (a) Use of testosterone, or dehydroepiandosterone (DHEA) in the last 3 months, or last 7 months in the case of hormonal implants (b) known severe psychiatric illness (c) uncontrolled hypertension, Systolic blood pressure (BP) > 160, Diastolic BP > 100 (d) pregnancy and lactation (e) serious endocrine disorder with systemic disease (f) alcohol consumption greater than 3 standard drinks per day (g) known acute or chronic liver disease (bilirubin > 26, alanine transferase > 100 U/L, alkaline phosphatase > 300 U/L) (h) Type 2 diabetes mellitus (T2DM), insulin dependent diabetes mellitus or use of an oral hypoglycemic agent (i) acute / chronic renal, liver, cardiovascular disease or any other chronic major illness which would impair overall health and wellbeing 2. Women who, in the opinion of the investigator, are a poor medical or psychiatric risk for treatment in a research protocol. 3. Women who have participated in a medical or surgical research protocol in the preceding 28 days.
研究者
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