跳至主要内容
临床试验/NCT03786705
NCT03786705已完成不适用

The Relationship of Delta Shock Index With the Requirement of Blood Transfusion and Clinical Outcome of Adult Trauma Patients

Chang Gung Memorial Hospital1 个研究点 分布在 1 个国家目标入组 7,957 人开始时间: 2018年6月5日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
7,957
试验地点
1
主要终点
in-hospital mortality

研究概览

简要总结

Background: To determine the performance of delta shock index (ΔSI), a change in shock index (SI) upon arrival at the emergency room (ER) from that in the field in predicting the need for massive transfusion (MT) among adult trauma patients with stable blood pressure.

Methods: This study included data from all trauma patients aged 20 years and above who were hospitalized from January 1, 2009 to December 31, 2016 and was obtained from the registered trauma database of the hospital. Only patients who were transferred by emergency medical service from the accident site with a systolic blood pressure ≥ 90 mm Hg at the ER were included in this study. The 7,957 enrolled trauma patients were divided into 2 groups, those who had received blood transfusion ≥ 10 U (MT, n = 82) and those who had not (non-MT, n = 7,875). The odds ratios with 95% confidence intervals for associated patient conditions and the odds of need for MT by a given ΔSI were measured. The plot of specific receiver operating characteristic (ROC) curves was used to evaluate the best cutoff point that could predict the patient's probability of receiving MT.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Retrospective

入排标准

年龄范围
20 Years 至 100 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Patients who were transferred by emergency medical service (EMS) from the field of accident and had a stable blood pressure (SBP ≥ 90 mmHg) at the ER were included

排除标准

  • Patients who were transferred from other hospitals or arrived by private vehicles.
  • Patients who had incomplete data
  • Patients who had an unstable blood pressure (SBP < 90 mmHg) upon arrival at the ER were also excluded

结局指标

主要结局

in-hospital mortality

时间窗: up to 5 months

To measure the outcome of patients.

次要结局

未报告次要终点

研究者

发起方
Chang Gung Memorial Hospital
申办方类型
Other
责任方
Sponsor

研究点 (1)

Loading locations...

相似试验