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临床试验/NCT04682938
NCT04682938已完成不适用

The Prevalence and Characteristics of Adrenal Incidentaloma: A Prospective Study

Chongqing Medical University1 个研究点 分布在 1 个国家目标入组 25,356 人开始时间: 2020年11月20日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
25,356
试验地点
1
主要终点
Prevalence and Characteristics of Adrenal Incidentaloma

研究概览

简要总结

To investige the prevalence, characteristics and prognosis of adrenal incidentalomas in Chinese adults.

详细描述

With the development of imaging detection technology and its wide application in clinic, the detection rate of adrenal incidentaloma (AI) has been greatly improved. Most AI are benign and do not have the function of autonomic hormone secretion, but about 20% of them have function and can secrete adrenal hormone autonomously. Studies based on biopsy reports show that the prevalence of AI is about 2%, and the prevalence of AI detected by CT scan is 1% - 4.5%. However, most of these studies are retrospective, and there may be selection bias and other confounding factors. There is no large sample prospective study on the prevalence of AI in the general population. The purpose of this study is to prospectively include patients with adrenal incidentaloma in community physical examination population, and evaluate their function and prognosis. The research results will provide new evidence for standardized diagnosis and treatment of adrenal incidentaloma in the future.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
18 Years 至 78 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • ·On weekdays, the first 100 individuals, aged 18 to 78 years, taking health checkup in the Community Health Examination Center were invited to take part in the study.

排除标准

  • with known adrenal diseases;
  • with continuous steroids or drug treatment that might influence cortisol secretion ordexamethasone metabolism and could not be stopped
  • refuse to participate in the study.

结局指标

主要结局

Prevalence and Characteristics of Adrenal Incidentaloma

时间窗: 1 years

To investigate the prevalence and characteristics of Adrenal Incidentaloma in general population in China

次要结局

  • Steroid hormones in the function of Adrenal Incidentaloma(1 years)

研究者

发起方
Chongqing Medical University
申办方类型
Other
责任方
Principal Investigator
主要研究者

Qifu Li

Prof.

Chongqing Medical University

研究点 (1)

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