NCT02414412已完成3 期
Immunity Improvement Effect of Ulmus Macrocarpa Water Extract in Adults
适应症
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 入组人数
- 58
- 主要终点
- serum natural killer cell activity
研究概览
简要总结
This randomized, placebo-controlled, double-blind study evaluates the efficacy and tolerability of Ulmus macrocarpa water extract for immunity improvement in relatively healthy adults. 58 subjects received 500 mg of Ulmus macrocarpa water extract per day or a placebo for 4 weeks.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Triple (Participant, Care Provider, Investigator)
入排标准
- 年龄范围
- 19 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •subject has peripheral white blood cells between 4,000/Ul and 8,000/Ul
排除标准
- •History of renal disease
- •History of diabetes mellitus
- •History of immune disease
结局指标
主要结局
serum natural killer cell activity
时间窗: 1 month
次要结局
- peripheral white blood cell(1 month)
- serum tumor necrosis factor-alpha level(1 month)
- serum interferon-gamma(1 month)
- serum interleukins(1betta, 2,4,8,10, and 12)(1 month)
研究者
Sang Yeoup Lee
professor
Pusan National University Hospital
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