The Effect of Detrusor Underactivity in Determining Outcomes After Transurethral Resection of the Prostate for Treatment of Benign Prostatic Hyperplasia
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 90
- 主要终点
- Restore spontaneous voiding
研究概览
简要总结
The aim of this clinical trial is to evaluate the effect of detrusor underactivity on the functional and symptomatic outcomes following transurethral resection of the prostate (TURP) in benign prostatic hyperplasia patients presenting with chronic urinary retention.
The main questions it aims to answer are:
Will they restore spontaneous voiding?
They will be divided into 2 comparative groups (each group 45 patients) based on detrusor contractility.
- Group (A) consists of patients with normal detrusor (bladder contractility index more than 100).
- Group (B) consists of patients with underactive detrusor (bladder contractility index less than 100).
研究设计
- 研究类型
- Interventional
- 分配方式
- Non Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 50 Years 至 —（Adult, Older Adult）
- 性别
- Male
- 接受健康志愿者
- 否
入选标准
- •Age: more than 50-year-old
- •Chronic urinary retention secondary to BPH
- •Prostate size Above 30 and less than 100gm
排除标准
- •Prostate size over 100 gm and less than 30 gm
- •Prostatic carcinoma
- •Urinary bladder carcinoma
- •Acute urinary retention
- •Urethral stricture.
- •Previous bladder, urethral or prostate surgery.
- •Acute urinary tract infection.
- •Neurogenic bladder
研究组 & 干预措施
consists of patients with underactive detrusor (bladder contractility index less than 100).
• Group (B) - Underactive Detrusor
干预措施: transurethral resection of Prostate (Procedure)
consists of patients with normal detrusor (bladder contractility index more than 100).
• Group (A) - Normal detrusor
干预措施: transurethral resection of Prostate (Procedure)
结局指标
主要结局
Restore spontaneous voiding
时间窗: 3 months
All the included patients in this study are urethral catheter-dependant pre-operatively and have very bad voiding parameters. we will assess how they will benefit after TURP by regaining spontaneous voiding without the need for urethral catheters any more.
次要结局
- Flow rate improvement(3 months)
- Post voiding residual urine volume decrease(3 months)
研究者
samir sherif
Principal Investigator
Ain Shams University