Evaluation of the Consumption of Probiotics on the Bacteria Causing Dental Caries: A Randomised Clinical Trial
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 入组人数
- 40
- 主要终点
- counts of streptococcus mutans after the consumption of probiotic
研究概览
简要总结
Dental caries is a multifactorial disease effecting majority of the human population.One of the etiological factor causing dental caries is salivary mutans streptococci. Reducing the levels of this bacteria in the saliva can significantly reduce the incidence of dental caries. A non-invasive intervention, such as the administration of probiotics reduced the salivary mutans streptococci levels.
详细描述
40 candidates were selected from a pre-determined group and were randomly assigned to two groups. Group A (n=20) was administered probiotic drink and Group B (n=20) was administered placebo for 14 consecutive days. Saliva was collected on day 1 and day 15 to compare the salivary mutans streptococci levels.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 20 Years 至 25 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Decayed Missing Filled Surfaces less than or equal to 6
- •Brushes twice daily
排除标准
- •undergoing orthodontic treatment
- •topical fluoride therapy in the past 2 yrs
- •using sugar free gums
结局指标
主要结局
counts of streptococcus mutans after the consumption of probiotic
时间窗: 15 days
Human saliva was assessed for the counts of streptococcus mutans, one of the major etiological factor for dental caries
次要结局
未报告次要终点
研究者
G.RATNA VELUGU
Assistant Professor
Sharda University