NCT00918541已完成不适用
Natural 1-year History of Atherosclerosis in Asymptomatic Patients With Mild to Moderate Carotid Stenosis
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 3
- 主要终点
- Progression of atherosclerotic plaque
研究概览
简要总结
20 patients will be recruited. The aim of the study is to determine the natural progression of atherosclerotic disease.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •stable carotid artery disease not requiring revascularization
- •asymptomatic carotid artery stenosis < 80% or symptomatic patients with stenosis < 60 %
- •prophylactic therapy with aspirin (> 100mg/day, statin, blood pressure therapy if indicated (goal < 130/80 mmHg))
- •informed consent
排除标准
- •non atherosclerotic occlusive disease (Bürgers disease)
- •uncontrolled BP (DBP > 110 mmHg and/or SBP > 200 mmHg)
- •hemorrhagic disease or platelet count < 100'000 mm^3
- •Known active liver disease (elevations of GPT GOT or increased ammonia)
- •impaired renal function (crea > 180 mmol/l)
- •pregnancy
- •severe claustrophobic reactions
- •short - term life - threatening pathology
- •physically unable to participate in the study
- •compliance not guaranteed
结局指标
主要结局
Progression of atherosclerotic plaque
时间窗: 12 months
次要结局
未报告次要终点
研究者
研究点 (3)
Loading locations...
相似试验
已完成
不适用
Investigation of the progression of atherosclerosis and atherosclerotic risk factor in patients with diabetesDiabetesJPRN-UMIN000014765Division of diabetes, Mitsui Memorial Hospital700
已完成
不适用
Prospective observational study of atherosclerosis progression in chronic kidney diseasechronic kidney diseaseJPRN-UMIN000015066Department of Nephrology and Hypertension, Internal Medicine, St. Marianna University School of Medi200
尚未招募
不适用
Analysis for regression of atherosclerosis in acute coronary syndrome patients after PCSK9 inhibitor therapy by using near-infrared spectroscopy and intravascular ultrasoundJPRN-UMIN000027238Kyoto Prefectural University of Medicine50
已完成
不适用
Progression of Sub-Clinical AtherosclerosisCardiovascular DiseasesHeart DiseasesCarotid Artery DiseasesAtherosclerosisNCT00241787Tufts Medical Center2,900
已完成
不适用
A Study of Atherosclerosis in Patients After Radiation Treatment for Breast CancerAtherosclerosisNCT00960401Winthrop University Hospital20