跳至主要内容
临床试验/NCT02073370
NCT02073370Unknown不适用

Clinical Evaluation, Biomarkers and Metabolomics of Sarcopenia in Frail Older Adults at Ambulatory Clinics

National Taiwan University Hospital1 个研究点 分布在 1 个国家目标入组 350 人开始时间: 2011年1月最近更新:
适应症

试验速览

阶段
不适用
入组人数
350
试验地点
1
主要终点
Domestic operation tool of sarcopenia for older adults

研究概览

简要总结

Sarcopenia related mobility dysfunction was a preventable presentation in transitional variation of frailty. However, the definition, associated risk factors, clinical course and outcome of sarcopenia in Taiwanese older adults are still under-clarified and need for further study.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Prospective

入排标准

年龄范围
65 Years 至 —(Older Adult)
性别
All
接受健康志愿者

入选标准

  • functional decline in recent one year
  • cognitive impairment
  • depressive symptom
  • mobility impairment
  • fall in recent one year
  • eating or feeding problems
  • weight loss
  • co-morbid conditions≧5
  • tracking by different physician ≧3 in recent half year
  • poly-pharmacy≧8 in recent 3 months
  • hospitalization ≧1 in recent one year
  • emergency visits≧2 in recent one year
  • aged ≧ 80.

排除标准

  • non-ambulatory (bed-ridden) patients
  • long-term residents at nursing homes
  • patients with a life expectancy shorter than six months
  • impairment in vision, hearing, or communicative ability, making convenience of clinical evaluation during the study period impossible.

结局指标

主要结局

Domestic operation tool of sarcopenia for older adults

时间窗: Baseline

Young health adults are recruited for measurement of body composition using bio impedance analysis in order to establish the norm of skeletal muscle index

次要结局

  • Change from baseline in body composition during aging(up to 2 years)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (1)

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