A Ten-year Practice of Labor Pain Control in China
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 40,000
- 试验地点
- 1
- 主要终点
- Rate of cesarean delivery
研究概览
简要总结
Since 1999, labor pain control has being performed in China, and the initial time of analgesia is at the cervix >= 2 cm. Meanwhile, American Society of Obstetrics & Gynecology recommended that the labor analgesia with neuraxial block should be performed at the cervix >= 4 cm in 2002. After that, the threshold has been revised to at least >= 2 cm in 2006 by the Society. However, in China, the practice of labor analgesia with neuraxial block has being performed for over seven years. Up until now, the practice has being experienced during this ten-year period at the cervix around 1 cm. The investigators hypothesized that labor pain control in different stages had different characteristics and had different influence on patients short- and long-lasting outcomes. This study is mainly investigating different labor analgesia procedures in different stages since the initiation of the practice in 1999, and assessing their influence on the outcomes to display the trajectory of development of labor analgesia in China of which might fit to the the whole process of the study of labor analgesia throughout the world. All these were done by analyzing the data records since from January 1999 to December 2008.
研究设计
- 研究类型
- Observational
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 45 Years（Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •Parturients used labor analgesia
排除标准
- •Following criteria were based on the records of information received from the ten-year practice screened by investigators:
- •Chronic pain and psychiatric diseases records
- •Participants younger than 18 years or older than 45 years
- •Alcohol addictive or narcotic dependent patients were excluded for their influence on the analgesic efficacy of the epidural analgesics
- •Subjects with a nonvertex presentation or scheduled induction of labor
- •Diagnosed diabetes mellitus and pregnancy-induced hypertension
- •Twin gestation and breech presentation
结局指标
主要结局
Rate of cesarean delivery
时间窗: Analgesia initiation to successful vaginal delivery
次要结局
- Rate of instrument-assisted delivery(Analgesia initiation to successful vaginal delivery)
- Indications of cesarean delivery(Analgesia initiation to cesarean section)
- Maternal Visual Analog Scale (VAS) rating of pain(Prior to analgesia, latent phrase, active phrase, second stage of labor, posterior to vaginal delivery)
- Duration of analgesia(Initiation of analgesia to the disappearance of sensory block)
- Maternal satisfaction with analgesia(At the end of the vaginal delivery)
- Maternal oral temperature(Analgesia initiation to successful vaginal delivery)
- Use of oxytocin after analgesia(After analgesia to vaginal delivery)
- Low back pain at 3 months after vaginal delivery(At the third month after vaginal delivery)
- Breastfeeding success at 6 weeks after vaginal delivery(At the sixth week after successful delivery)
- Neonatal one-minute Apgar scale(At the first minute of baby was born)
- Neonatal five-minute Apgar scale(At the fifth minute of baby was born)
- Incidence of maternal side effects(Analgesia initiation to successful vaginal delivery)
- Umbilical-cord gases analysis(At the time baby was born)