People's Hospital of Xinjiang Uygur Autonomous Region
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 160
- 试验地点
- 1
研究概览
简要总结
Objective: To evaluate the impact of enhanced recovery after surgery (ERAS)-based nursing intervention on venous thromboembolism (VTE) and lymphedema after radical hysterectomy for cervical cancer.
Methods: In this prospective randomized controlled trial, 160 patients scheduled for radical hysterectomy during September 2022-September 2024 were randomized to an ERAS group (n = 80) or a control group (n = 80). The control group received conventional perioperative care, while the ERAS group received a multimodal perioperative care protocol. Primary outcomes were the 6-month incidence of VTE and lower limb lymphedema. Secondary outcomes included recovery indicators, inflammatory and coagulation markers, quality of life [QoL; assessed by the Quality of Life Questionnaire-Core 30 (QLQ-C30)], and nursing satisfaction.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 70 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •. Pathologically confirmed cervical cancer (FIGO 2018)
- •Age 18-70 years
- •First-time radical hysterectomy
- •ASA physical status class I-II
- •Perioperative anticoagulant prophylaxis per hospital standards
- •Provision of informed consent
排除标准
- •1. Pre-existing lower extremity DVT, lymphedema, or severe varicose veins
- •Severe cardiac, hepatic, or renal dysfunction or coagulation disorders
- •History of psychiatric illness or communication barriers
- •Pregnant or lactating women
研究者
Xiumin Zhang
Principal Investigator
People's Hospital of Xinjiang Uygur Autonomous Region