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临床试验/NCT06890455
NCT06890455尚未招募不适用

Fecal Calprotectin in Patients Infected with Intestinal Protozoan Infections

Sohag University1 个研究点 分布在 1 个国家目标入组 120 人开始时间: 2025年3月最近更新:

试验速览

阶段
不适用
状态
尚未招募
入组人数
120
试验地点
1
主要终点
Prevalence of Blastocystis and Entamoeba

研究概览

简要总结

Calprotectin extracted from stool can be detected easily using ELISA. Numerous studies have shown that fecal calprotectin concentrations demonstrate a good correlation with intestinal inflammation This study aims to detect the relationship between fecal calprotectin and Blastocystis hominis and Entamoeba histolytica infections.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Other

入排标准

性别
All
接受健康志愿者

入选标准

  • 120 fecal samples will be collected as the following:
  • 40 samples from patients complaining of gastrointestinal manifestations and only infected with B.hominis and E.histolytica.
  • 40 samples from patients complaining of gastrointestinal manifestations without any protozoal infection.
  • 40 healthy control cross-matched volunteers (without gastrointestinal manifestations, or intestinal parasites).

排除标准

  • persons received antiparasitic drugs or antibiotic 2 weeks before sample collection Patients with mixed intestinal protozoa Patients with intestinal protozoa rather than Entamoeba histolytica and Blastocystis

结局指标

主要结局

Prevalence of Blastocystis and Entamoeba

时间窗: 2 months

次要结局

  • Number of persons have high fecal calprotectin(6 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

Youstina Kamel Boles

Demonstrator of Medical parasitology

Sohag University

研究点 (1)

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