JPRN-jRCTs061180053已完成2 期
A clinical study evaluating the effectiveness of Lactobacillusvaginal suppositories in patients with recurrent urinary tract infection - A study evaluating the effectiveness of Lactobacillus vaginal suppositories in recurrent urinary tract infection
ISHII AYANO0 个研究点目标入组 28 人开始时间: 2019年3月14日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 28
研究概览
简要总结
Patients with recurrent cystitis were instructed to insert one vaginal suppository for 1 year. 21 completed the study. The mean patient age was 68.3. The number of recurrences of cystitis could be suppressed by 70% or more were 9 of the 21(43%) patients and 13 (62%) patients, during and after administration each other.The median number of recurrences of urinary tract infections was a significant reduction . In some cases, L. crispatus could be confirmed from the vagina. No adverse events were observed.
研究设计
- 研究类型
- Interventional
入排标准
- 年龄范围
- >= 20age old 至 ot applicable（—）
- 性别
- Female
入选标准
- •1) Acute simple cystitis
- •2) Acute exacerbation of chronic complicated cystitis occurring in patients using clean intermittent catheterization
- •3) Acute exacerbation of chronic complicated cystitis in neurogenic bladder and overactive bladder with residual urine volume of 50 mL or less
- •4) Other acute exacerbations of chronic complicated cystitis occurred in mild basic disease of the urinary tract
- •The episode of urinary tract infection in need of intervention corresponding to any one of the above 1) to 4) has been found twice or more in the recent 1 year and the female patients of below 1) to 3)
- •1) Patients who have already completed treatment with urinary tract infection antibiotics
- •2) Patients over 20 years old
- •3) Outpatient(Non-hospitalized patient)
排除标准
- •1) Patients requiring urological treatment such as urolithiasis, hydronephrosis, urinary tract tumors
- •2) Patient indwelling urethral catheter
- •3) Patients with severe underlying disease and complications such as poorly controlled diabetes, collagen disease, leukemia, advanced cancer, congestive heart failure, severe liver or renal dysfunction
- •4) Patients who had seen allergic hypersensitivity symptoms by ingestion of dairy products or lactobacillus products in the past
- •5) Patients who have sex partner, whose partner have had allergic hypersensitivity symptoms by ingestion of dairy products or lactobacillus products in the past
- •6) Patients who wish to have babies within one year and patients who are pregnant
- •7) Patients who were judged inappropriate as subjects of this study by doctors
研究者
相似试验
已完成
不适用
Randomized Phase II trial of single early intravesical administration of THP for prevention of recurrent bladder tumors following surgery for upper urinary tract urotherial tumors.pper urinary tract urotherial tumorJPRN-UMIN000004039Tohoku University School of Medicine,Department of Urology50
撤回
不适用
Evaluate The Effectiveness Of Fospropofol (Lusedra®) For Induction Of AnesthesiaInterstitial CystitisNCT01378754Grace Shih, MD
已完成
2 期
Immunomodulatory treatment of recurrent cystitis - An open label, randomized, single-center, phase II trialncomplicated recurrent lower urinary tract infection in female patientsDRKS00025964SelectImmune Pharma AB (Lund, Schweden)Org nr: 559104-687430
已完成
3 期
Efficacy Study of Adalimumab to Treat Interstitial CystitisInterstitial CystitisNCT01295814ICStudy, LLC43
Unknown
不适用
Prospective Trial to Evaluate Efficacy and Accuracy of a Portable Ultrasound Scanner for Non-Invasive Bladder Volume Measurement (BladderScan BVI3000) in Patients After Radical Cystectomy and Bladder ReconstructionBladder SubstitutionReconstructed BladderNCT00512174Sheba Medical Center