Diurnal Intraocular Pressure and Peripapillary Retinal Blood Flow in Medically Controlled Open-Angle Glaucoma
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 70
- 试验地点
- 1
研究概览
简要总结
Diurnal fluctuations of intraocular pressure (IOP) and peripapillary retinal blood flow may have distinctive patterns in medically well-controlled open-angle glaucoma patients. In the results, we found a unique pattern, 'Latent asymmetric IOP', defined as the IOP which differs between the eyes only when placed in the supine position. Unique effects of this latent asymmetric IOP on Visual field and diurnal IOP fluctuations were studied.
详细描述
Diurnal fluctuations of intraocular pressure (IOP) and peripapillary retinal blood flow have been implicated to be one of the important factors to affect visual field progression. However, there was no study to investigate them in medically well-controlled open-angle glaucoma patients. So we want to find the unique patterns.
Study 1. Subjects : Patients with medically well controlled open angle glaucoma Method : IOP and peripapillary retinal blood flow were measured for 24 hours. The relationship between the two were studied.
Study 2. Of the patients enrolled in study 1 , those on the same medical regimen for both eyes were analyzed for the presence of a latent asymmetric IOP and it's influence and association with visual field and diurnal IOP fluctuation.
研究设计
- 研究类型
- Observational
- 观察模型
- Natural History
- 时间视角
- Other
入排标准
- 年龄范围
- 20 Years 至 70 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Open-angle glaucoma
- •Topical anti-glaucoma medications
排除标准
- •Ocular surgery history
- •Other ocular disease history
- •Oral glaucoma medications