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临床试验/NCT03531801
NCT03531801已完成不适用

Pressure-induced Referred Pain is More Expansive in Individuals With a Recovered Non-painful Fracture

Universidad San Jorge1 个研究点 分布在 1 个国家目标入组 44 人开始时间: 2017年10月30日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
发起方
入组人数
44
试验地点
1
主要终点
A change in the area of referred rain

研究概览

简要总结

The purpose of the present study is to investigate pressure algometry and pressure-induced referred pain areas in pain free individuals with a history of distal radius fracture (fully recovered) compared with age and gender matched healthy controls without history of fracture. It is hypothesized that individuals with a recovered radius fracture will have a facilitated referred pain patter towards the wrist but normal pressure pain sensitivity.

详细描述

Musculoskeletal injuries, nociception and pain can increase the sensitivity of the central pain mechanisms, which can be extended even after tissue recovery. However, little is known about the status of these central pain mechanisms once subjects are fully recovered from the tissue injury and pain. This information would help to explain pain conditions in which recurrence of the pain episodes is common (e.g low back pain or shoulder pain).

Pressure-pain thresholds have been widely used in pain research to test the sensitivity of the pain system. Additionally, referred pain has been shown as a valid biomarker for the sensitization of the pain system.

The aim of the present study is to investigate pressure pain sensitivity and referred pain patterns of individuals with a history of recovered fracture, compared with healthy controls.

研究设计

研究类型
Observational
观察模型
Case Control
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 80 Years(Adult, Older Adult)
性别
All
接受健康志愿者

入选标准

  • Subjects with a history of distal radius fracture without pain at the moment of the study.

排除标准

  • Subjects with symptoms (e.g pain), functional limitations, history of other fractures in the upper limb or any other pathology.

结局指标

主要结局

A change in the area of referred rain

时间窗: 24 hours (two experimental sessions separated by 24h).

This outcome measure corresponds to the difference or change in the size and distribution of the pressure-induced referred pain area, between the two experimental sessions.

次要结局

  • A change in pressure-pain thresholds(24 hours (two experimental sessions separated by 24h).)

研究者

发起方
Universidad San Jorge
申办方类型
Other
责任方
Principal Investigator
主要研究者

Víctor Doménech

Lecturer and Researcher at Universidad San Jorge

Universidad San Jorge

研究点 (1)

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