The Involvement of Pudendal Somatic Afferents in Sacral Neuromodulation Assessed by Somatosensory Evoked Potentials of the Pudendal Nerve
试验速览
- 阶段
- 不适用
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Latency change
研究概览
简要总结
Sacral neuromodulation is a well-excepted minimally invasive procedure for the treatment of overactive bladder and non-obstructive urinary retention.A tined lead with 4 stimulation electrodes is placed through the third or fourth sacral foramen and stimulates sacral roots in its vicinity. Since the sacral roots are mixed nerves, it is currently still unknown which nerve fibers are stimulated (autonomic vs somatic, afferent vs efferent) and what the mechanism of action is.
This study examines the involvement of pudendal somatic afferents by measuring somatosensory evoked potentials elicited by stimulation of the pudendal nerve.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Overactive bladder
- •Non-obstructive urinary retention
排除标准
- •Neurogenic disorders (e.g. cerebrovascular accident, spinal cord injury,...)
结局指标
主要结局
Latency change
时间窗: 3 weeks
Latency of somatosensory evoked potential are recorded before and after test procedure sacral neuromodulation expressed in milliseconds.
次要结局
未报告次要终点
研究者
Donald Vaganée
MD, PhD student
Universiteit Antwerpen