Head and Neck Tumor Tissue Repository and Clinical Database
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 入组人数
- 8,000
- 试验地点
- 4
- 主要终点
- Maintenance of a clinical database pertaining to diagnosis and treatment outcome of patients with head and neck cancer
研究概览
简要总结
RATIONALE: Collecting and storing samples of tissue, saliva, and blood from patients with cancer and from healthy participants to study in the laboratory may help the study of cancer in the future.
PURPOSE: This research study is collecting and storing tissue samples from patients with head and neck cancer and from healthy participants.
详细描述
OBJECTIVES:
- Maintain and update a clinical database pertaining to diagnosis and treatment outcome of patients with head and neck cancer.
- Develop a repository of biospecimens from these patients.
OUTLINE: Tumor tissue samples and/or bronchial washings are collected from patients undergoing planned surgery and/or bronchoscopy, respectively. Buccal swabs and/or mouthwash samples and saliva samples are collected. Patients also undergo blood sample collection at baseline and then every 2-6 months thereafter.
Healthy participants contribute blood samples, buccal swabs, and mouthwash samples at baseline only.
Information about medical and family history and cancer risk factors is also collected.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Cross Sectional
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- 未提供
排除标准
- 未提供
结局指标
主要结局
Maintenance of a clinical database pertaining to diagnosis and treatment outcome of patients with head and neck cancer
时间窗: ongoing
Collection of data for both groups from the Vanderbilt Otolaryngology Patient Intake questionnaire as well as the medical record, such as medical history, family history, and exposures to risk factors for cancer (tobacco and alcohol use), and results of tests related to diagnosis of tumor and treatment response (for tumor patients only).
Development of a repository of biospecimens
时间窗: ongoing
Collection of blood, tissue, saliva, bronchial washings and other specimens as indicated from both tumor and healthy patients.
次要结局
未报告次要终点
研究者
Eben Rosenthal
Dept Chairperson Professor
Vanderbilt University Medical Center