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临床试验/NCT04155775
NCT04155775已完成不适用

Effects of a Platelet Transfusion Best Practices Alert

Stanford University2 个研究点 分布在 1 个国家目标入组 446 人开始时间: 2019年5月9日最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
446
试验地点
2
主要终点
Platelet transfusions above threshold

研究概览

简要总结

This study is to determine the effectiveness of a computerized clinical decision support tool (Best Practice Alert - BPA) in reducing unnecessary platelet transfusions based on guidelines published by national transfusion societies such as the AABB (formerly American Association of Blood Banks).

详细描述

A computerized alert will be deployed through the electronic health record. The alert will trigger when a provider orders platelet transfusion above a threshold supported by current guidelines. The alert will provide information on current evidence and give the provider the option to cancel the order or proceed. The alert will not be triggered in procedural areas such as the operating room or as part of any emergency orders to prevent any delays to urgent patient care.

The proposed project will evaluate this alert by randomizing its implementation by patient chart. The investigators will observe the prevalence of this alert and its impact on ordering practices for the next 3 months. For patient charts randomized not to receive the intervention, the providers will not receive any alerts, but the analytics tool will record if the alert would have been triggered and the pertinent clinical information. After a period of three months, the investigators will review patient and provider information through analytics tools, assessing differences in platelet usage between the patients whose charts showed the alerts vs. those (control) patient charts not showing alerts.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Parallel
主要目的
Other
盲法
None

入排标准

性别
All
接受健康志愿者

入选标准

  • Recent platelet count >50k/uL
  • Platelet transfusion ordered

排除标准

  • Neurosurgery
  • Procedure area (OR, catheterization lab, interventional radiology suite)
  • Documented history of antiplatelet agent

结局指标

主要结局

Platelet transfusions above threshold

时间窗: Data will be initially reviewed before 6 months from start with anticipated completion 1 year from start

Number of platelet transfusions occurring in patients with recent platelet counts above 50k/uL

次要结局

  • Total platelet transfusions(Data will be initially reviewed before 6 months from start with anticipated completion 1 year from start)

研究者

申办方类型
Other
责任方
Sponsor

研究点 (2)

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