Validating Transesophageal Echocardiographic Measurements of Right Ventricular Function
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 126
- 试验地点
- 1
- 主要终点
- Tricuspid annular plane systolic excursion (TAPSE)
研究概览
简要总结
Transesophageal echocardiography (TEE) is becoming a more prevalent method of monitoring and diagnosis in the perioperative setting for critically ill patients and patients undergoing cardiac surgery. Many TEE measurements are extrapolated from transthoracic echocardiography (TTE) data and have not validated by transesophageal means. The aim of this study is to validate TEE assessment of right ventricular function by comparing them to simultaneously measured TTE measurements.
Likewise, there are currently no agreed upon values for RV free wall strain. Therefore, the investigators will attempt to define a range of normal values of RV free wall strain as compared to the other measures of RV function.
详细描述
Traditionally, all echocardiographic measurements have been studied utilizing TTE. Therefore the normal values and ranges for pathology findings have been defined by transthoracic means alone. TEE offers different images planes when compared to TTE, which may make the measurements obtained differ from those obtained by TTE. In the operating room environment the vast majority of echocardiography is completed by transesophageal means for many reasons; largely access to the patient and the continuous use of TEE as a hemodynamic monitor. However, given the fact that most echocardiographic measurements have only been validated by TTE, there remains a question as to the validity or precision of TEE-derived measurements.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients undergoing elective cardiac surgery requiring TEE
排除标准
- •Patient who do not wish to consent
- •Patients with contraindications to TEE
- •Urgent or emergent cardiac surgery
- •Patients with preexisting open chest
- •Patients with intrathoracic hardware (VAD, thoracostomy tube, etc)
- •Non-English speaking subjects
- •Cognitively impaired adults
- •Pregnancy
结局指标
主要结局
Tricuspid annular plane systolic excursion (TAPSE)
时间窗: Immediately following the induction of anesthesia and TEE probe placement
Tricuspid annular plane systolic excursion (TAPSE) will be measured using both TTE and TEE.
Right ventricular fractional area change (FAC)
时间窗: Immediately following the induction of anesthesia and TEE probe placement
Right ventricular fractional area change (FAC) will be measured using both TTE and TEE.
RV free wall longitudinal strain
时间窗: Immediately following the induction of anesthesia and TEE probe placement
RV free wall longitudinal strain will be measured using both TTE and TEE.
Right ventricular index of myocardial performance (RIMP)
时间窗: Immediately following the induction of anesthesia and TEE probe placement
Right ventricular index of myocardial performance (RIMP) will be measured using both TTE and TEE.
RV annular systolic velocity (S')
时间窗: Immediately following the induction of anesthesia and TEE probe placement
RV annular systolic velocity (S') will be measured using both TTE and TEE.
次要结局
- Ease of obtaining appropriate TEE measures of right ventricular function(Within 15 minutes following anesthesia induction)
- Define values for normal right ventricular free wall strain(Through study completion, an estimate of 1 year)
研究者
Shayne Michael Roberts
Assistant Professor
Milton S. Hershey Medical Center