Evaluation of Desensitizing Effects of 10% Potassium Nitrate and Gluma Primer in Treating Dentinal Hypersensitivity- A Split Mouth, Double Blind, Preliminary Randomized Control Trial.
试验速览
- 阶段
- 1/2 期
- 状态
- 尚未招募
- 入组人数
- 100
- 试验地点
- 1
- 主要终点
- Reduction in clinical signs and symptoms of dentine hypersensitivity.
研究概览
简要总结
Potassium nitrate was introduced as a desensitizing agent. Potassium nitrate is supposed to reduce hypersensitivity by inducing a sustained depolarization of nerve membrane. It has also been postulated that blockage of dentinal tubules by potassium nitrate reduces sensitivity.
Gluma® is a commercially available desensitizing agent which is known to occludes dentinal tubules by coagulation of amino acids and proteins present in the dentin.
There are no studies evaluating the desensitizing effects of 10% potassium nitrate compared to gluma primer. The present study aims to compare and evaluate their effectiveness in the treatment of dentine hypersensitivity.
研究设计
- 研究类型
- Interventional
- 分配方式
- Coin toss, Lottery, toss of dice, shuffling cards etc
- 盲法
- Participant and Investigator Blinded
入排标准
- 年龄范围
- 35.00 Year(s) 至 70.00 Year(s)（—）
- 性别
- All
入选标准
- •1.History of hypersensitivity 2.No other treatments received for hypersensitivity, at least 2 months prior to this trial.
- •3.Clinical evaluation of exposed occlusal dentine bilaterally I,e., attrition.
- •4.Patients with 35-70 years age groups.
- •5.Home care oral hygiene instructions standardized.
排除标准
- •1.Caries or restoration in relation to hypersensitive teeth.
- •2.Enamel cracks or pulpitis.
- •3.Cervical abrasions and erosions.
- •4.History of periodontal surgeries within past 6 months.
结局指标
主要结局
Reduction in clinical signs and symptoms of dentine hypersensitivity.
时间窗: Weekly intervals i.e, 1st week, 2nd week, 3rd week, 4th week and 5th week.
次要结局
- Compare desensitising effects of 10% potassium nitrate and Gluma® primer in treating dentinal hypersensitivity.(5 weeks)