Critical Care Observation of Motor Activity (COMA) - A Practicable and Valid Predictor of Patients' Outcome in the Surgical Intensive Care Unit: A Observational Study at 2 Surgical Intensive Care Units at Massachusetts General Hospital
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 761
- 试验地点
- 1
- 主要终点
- Adverse discharge disposition
研究概览
简要总结
In the surgical intensive care unit (SICU), goals of critical care are often discussed in long-term ventilated patients around the time of extubation. Muscle weakness predicts extubation failure but formal muscle strength assessment by the Medical Research Council scale is time-consuming and not part of the daily clinical exam. In this observational study, we hypothesize that COMA measurement, routinely used by the SICU nurses, is a reliable and valid predictor for patients' SICU outcomes. This prospective observational study is carried out within a consecutively enrolled cohort of adult patients who are extubated in two SICUs at Massachusetts General Hospital, Boston.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 112 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Intubated and mechanically ventilated patients in 2 ICUs at Massachusetts General Hospital
- •adult patients
排除标准
- •Tracheostomy without extubation attempt
- •Death without extubation attempt/terminal extubation
结局指标
主要结局
Adverse discharge disposition
时间窗: Within one day after hospital discharge
次要结局
- ICU length of stay(Time frame within 24 hours after ICU admission and within 24 hours after ICU discharge)
- 30-day mortality(Within 30-days after extubation in the ICU or until the day of hospital discharge)
- 30-day hospital readmission(Within 30 days after discharge from the index hospital stay)
- Hospital length of stay(Time frame within 24 hours after hospital admission and within 24 hours after hospital discharge)
- Hospital costs(Between the day of hospital admission and the day of hospital discharge)
研究者
Matthias Eikermann
Dr.
Massachusetts General Hospital