The Effect of CBT- Based Weight Loss Program on Eating Behavior, Weight Loss Result and Risk for Coronary Heart Diseases and Type 2 Diabetes
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 62
- 试验地点
- 1
- 主要终点
- change in weight
研究概览
简要总结
The investigators purpose is to study how CBT (cognitive behavioral therapy)-based weight loss program affects on eating behavior, weight loss and risk factors for CHD (coronary heart diseases)and type 2 diabetes. Moreover, the investigators aim is to recognize subjects suffering from anhedonia (one of the core symptoms of depression, lack of pleasure) and follow how they benefit from the program in order to achieve maintained weight loss. Also, the associations between weight loss, physical activity and musculoskeletal disorders are studied.
详细描述
Obesity is an increasing problem and effective weight loss methods are needed. The study is randomized follow-up study with 9 months intervention and three (3) years follow-up period. The study is organized in Oulu University Hospital, Department of Internal Medicine. Eighty (80)obese, 20-65 years, study subjects will be randomized into intervention or control group.
The hypothesis of the CognObe study is: CBT (cognitive behavioral therapy)-based weight loss program is successful in sustained and favourable change in eating behavior and weight as well as decreased risk for coronary heart diseases or type 2 diabetes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 20 Years 至 65 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •BMI > 30
排除标准
- •other concurrent weight loss programs
- •disease which prevents weight loss
- •medication which affects on weight loss
研究组 & 干预措施
Weight loss counseling
Cognitive behavioral therapy - based weight loss program
干预措施: Cognitive behavioral therapy -based weight loss program (Behavioral)
Control
Short term weight loss counseling, control group
干预措施: Cognitive behavioral therapy -based weight loss program (Behavioral)
结局指标
主要结局
change in weight
时间窗: baseline, 9 months, 1,2 and 3 years
kilograms
次要结局
- change in total cholesterol,HDL, LDL,Trigly and glucose(baseline, 1,2 and 3 years)
- DNA(baseline)
- change in incretins(baseline, 12, 24 and 36 months)
- change in eating behavior(baseline, 9 months, 1,2 and 3 years)
研究者
Anna-Maria Keränen
P.h.D, clinical nutritionist
University of Oulu