Recurrent Campylobacter Bacteraemia in Immunocompromised Patients: a Retrospective Nationwide Study in France, 2000-2025
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 30
- 试验地点
- 1
- 主要终点
- Description of the characteristics of the patients presenting with recurrent Campylobacter bacteraemia
研究概览
简要总结
Some rare cases of recurrent Campylobacter bacteraemia (RCB) exist with relapses months to years after an effective treatment and a negativation of all bacterial samples.
As of today, only around 20 cases have been described in the international literature for the last 30 years. The cases are likely highly underreported.
No study describes those recurrent Campylobacter bacteraemias at the scale of a country.
The aim of this multicentre, nationwide, retrospective study is to describe their precise epidemiology in France for the last 25 years, the immune profile of the patients, the specificities of the bacteria involved, the treatments received and the evolution of these infections.
The perspective is to propose a standardization of the medical care of those patients mainly by describing the effective treatments and the explorations of the immune system which should be considered.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Retrospective
入排标准
- 年龄范围
- — 至 100 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •2 episodes or more of Campylobacter bacteraemia separated by at least 60 days
- •AND immunodeficiency condition
- •followed by a French hospital
排除标准
- •Opposition of the patient
结局指标
主要结局
Description of the characteristics of the patients presenting with recurrent Campylobacter bacteraemia
时间窗: Baseline
-characteristics of bacteraemia: clinical presentation, bacteria (species, antimicrobial susceptibility), secondary localizations, evolution, treatment modalities (antibiotics and immunother
次要结局
未报告次要终点