NCT04070170已完成不适用
The Effects of Lower Level Laser Therapy on Orthodontic Tooth Movement
Ildeu Andrade Jr.2 个研究点 分布在 1 个国家目标入组 24 人开始时间: 2014年2月1日最近更新:
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 24
- 试验地点
- 2
- 主要终点
- Rate of orthodontic tooth movement, with and without low-level laser therapy
研究概览
简要总结
The aims of this study will be to evaluate if a Lower Level Laser Therapy (LLLT): (1) enhances the levels of important pro-inflammatory chemokines involved in the bone remodeling process; (2) increases the rate of orthodontic tooth movement (OTM) on human subjects.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Quadruple (Participant, Care Provider, Investigator, Outcomes Assessor)
入排标准
- 年龄范围
- 13 Years 至 18 Years（Child, Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Facial convexity
- •Protrusion or biprotrusion of the incisors
- •Dental crowding
- •Healthy periodontal condition
- •Satisfactory oral hygiene
排除标准
- •Patients under medications that may interfere with bone metabolism, such as anti-inflammatory, antibiotics and hormonal supplements in the previous three months
- •Skeletal crossbite
- •Parafunctional habits
- •Occlusal interference
结局指标
主要结局
Rate of orthodontic tooth movement, with and without low-level laser therapy
时间窗: The quantification of OTM was performed after 3 months of canine retraction
The canine retraction was measured with a digital dynamometer
次要结局
- Chemokine levels in the periodontal tissue after LLLT and orthodontic force(The chemokine levels were assayed on days 0, 1, 7 and 14 after application of orthodontic force and low-level laser therapy)
研究者
Ildeu Andrade Jr.
Professor
Pontifícia Universidade Católica de Minas Gerais
研究点 (2)
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