NCT05223400已完成不适用
Drug Use Evaluation Study of Clindamycin in Critical Care Units in Alexandria Main University Hospital
适应症
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 99
- 试验地点
- 1
- 主要终点
- the number of prescriptions with appropriate indications of clindamycin will be counted during the retrospective observation of all prescriptions
研究概览
简要总结
Irrational use of antibiotics is a one of the main health system problems,it leads to antibiotic resistance,increasing antibiotics side effects and the total cost. This study is a medication use evaluation study aims to evaluate intravenous clindamycin prescribing practice in critical care units in Alexandria Main University Hospital.
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 100 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults 18 years old or more .
- •Patients on clindamycin as an empirical treatment.
- •Patients started clindamycin as an emperical treatment in other departments but the physician approved to continue it in critical care.
排除标准
- •Children (less than 18 years old)
- •Patients started clindamycin as a defenitive treatment (based on microbiological culture results).
结局指标
主要结局
the number of prescriptions with appropriate indications of clindamycin will be counted during the retrospective observation of all prescriptions
时间窗: 1 month
appropriateness of clindamycin indication will be determined according to IDSA guidelines.
次要结局
- the number of prescriptions with duplication of therapy with clindamycin will be counted during the retrospective observation of all prescriptions(1 month)
- the number of patients who had diarrhea as a main side effect of clindamycin(1 month)
- the number of patients who had severe drug interactions with clindamycin(1 month)
- to calculate the total cost of clindamycin.(1 month)
- Total clindamycin DDD defined daily doses and clindamycin defined daily doses per 1000 patients days.(1 month)
研究者
Heba Shaker
supervisor of clinical pharmacy unit in Alexandria Main University Hospital
Alexandria University
研究点 (1)
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