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临床试验/NCT01430338
NCT01430338已完成不适用

Different Metabolic Characteristics in the Presence of Brown Adipose Tissue in Humans

Korea University1 个研究点 分布在 1 个国家目标入组 90 人开始时间: 2010年12月最近更新:
适应症

试验速览

阶段
不适用
状态
已完成
入组人数
90
试验地点
1
主要终点
presence metabolic syndrome

研究概览

简要总结

Functional brown adipose tissue (BAT) exists in adult humans and can be detected by PET and especially during acute cold exposure. It is conceivable that BAT activity might reduce the risk of developing obesity since fat stores are used for thermogenesis, and a directed enhancement of adipocyte metabolism might have value in weight reduction. So it is important to know the different metabolic characteristics in human adults who have detected BAT. Therefore, the purpose of the investigators study is to compare different metabolic characteristics in the presence of brown adipose tissue in humans.

研究设计

研究类型
Observational
观察模型
Cohort
时间视角
Cross Sectional

入排标准

年龄范围
18 Years 至 —(Adult, Older Adult)
性别
Female
接受健康志愿者

入选标准

  • Patients who underwent 18FDG-PET/CT scan year between 2008-2010

排除标准

  • History of cardiovascular disease (myocardial infarction, unstable angina, stroke, or cardiovascular revascularization)
  • Stage 2 hypertension
  • Severe renal or hepatic disease

结局指标

主要结局

presence metabolic syndrome

时间窗: 5 months

次要结局

  • BMI(5 months)
  • sarcopenia(5 months)
  • visceral fat area(5 months)
  • adipokines(5 months)

研究者

申办方类型
Other
责任方
Principal Investigator
主要研究者

K. M. Choi

Professor

Korea University

研究点 (1)

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