Adolescent Depression Associated With Parental Depression : Screening, Prevalence and Secondary Prevention From the Meeting of Depressed Parents on Primary Care
试验速览
- 阶段
- 不适用
- 状态
- 终止
- 入组人数
- 80
- 试验地点
- 24
- 主要终点
- Changes in adolescents' depression intensity
研究概览
简要总结
Depression is difficult to identify, prevent and treat in adolescents because of complex and stigmatized multiform symptoms and pathways of care.
In children the existence of a parental depression is a significant and recognized risk factor for the development of a depression. It is regularly reported that 30% of adolescents of depressed parents have depression themselves. General Practitioners (GP) have significant access to the depression of adults, potentially parents of teenagers. In fact, 20% of patients in the regular active file of one GP have depression. The primary health care system could provide indirect but voluminous and unprecedented access to the identification of adolescent depression at an early stage from the encounter of depressed parents.
The difficulties of articulation between primary care (PC) and mental health devices are demonstrated. They disrupt the care pathways of adolescents detected in PC, prevention, and may even disturb early detection of depression. An organized joint between the PC and a specialized mental health service for adolescents ("Maison Des Adolescents" MDA) could promote the process of screening and preventing depression of adolescents of depressed parents encountered in PC.
In addition, if the effects of parental depression on adolescents are established, they remain complex and interactive. They vary by age and sex of the child but also the sex of the parent. A concomitant study of adolescent and parent depression will provide data to analyze the prevalence of depressed parent adolescent depression and to define risk or protection factors.
AdoDesP study is a cluster randomised trial (randomisation of the GPs) which compare a group of adolescent with PC articulated with mental health service (MDA) and an other group without articulation (routine cares).
A third group of depressed adolescents will be constituted to analyse parental depression of depressed adolescents.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 11 Years 至 —（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Parents of groups 1 and 2 :
- •Major patient consulting his GP
- •Depressed patient
- •Parent of adolescent aged between 11 and 18 years old
- •Adolescents of groups 1 and 2 :
- •Aged more than 11 and less than 18 years old
- •Parent included in the study
- •Parents of group 3 :
- •Parent of depressed adolescent under care at the MDA of Marseille, included in the study and whose depression is confirmed by HSCL25 scale
- •Adolescents of group 3 :
- •Aged more than 11 and less than 18 years old
- •Depressed patient
- •Under care at the MDA of Marseille since less than 1 month
排除标准
- •Parents of groups 1, 2 and 3 :
- •Minor patient
- •Enable to give his consent
- •Patient with guardianship or curatorship
- •Non consenting patient
- •Pregnant or nursing mother
- •Adolescents of groups 1 and 2 :
- •Aged < 11 or ≥18
- •Parent whose depression isn't confirmed by HSCL25 scale
- •Non consenting adolescent
- •Pregnant or nursing mother
- •Adolescent of group 3 :
- •Aged < 11 or ≥18
- •Non depressed adolescent
- •Non consenting patient
- •Pregnant or nursing mother
结局指标
主要结局
Changes in adolescents' depression intensity
时间窗: Day 0 and Month12
The depression intensity will be evaluated by Adolescent Depression Rating Scale (ADRS) at Day 0 and Month 12. The investigators will compare its evolution between group 1 (PC articulated with MDA) and 2 (Routine cares). Adolescent depression rating scale (ADRS) assesses depression in adolescents in 10 items. The items measure insomnia, anxiety, sadness and fatigability. If ADRS score is less than 4 : low risk of depression, between 4 and 8 : moderate risk of depression and more than 8 : significant risk of depression.
次要结局
- Prevalence of adolescent depression with depressed parent(Day 0)
- Diagnosis of depression rate(Day 0)
- Risk and protection factors(Day 0)
- Changes in adolescents' quality of live(Day 0, Month6 and Month12)
- Prevalence of parental depression with depressed adolescent(Day 0)