Laser Hemotherapy Trial for Coronary Artery Disease Prevention in High Risk Patients
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 50
- 试验地点
- 2
- 主要终点
- changes of blood pressure
研究概览
简要总结
This study will evaluate the effect of low level laser blood radiation applied to all participants for prevention of coronary artery disease in patients with high risk (hypertension,high blood viscosity, hypercholesterolemia as well as related immune issues)
详细描述
The areas of low - intensity laser use have expanded in several conditions by different mechanisms and ways. Hypertension as one of coronary artery disease risk factors and early indicator of future cardiovascular events with high blood viscosity and elevated blood cholesterol levels with immune-pathological basis became necessary issue to be handled. Low Level Laser irradiation effects on blood is very essential way in revealing the mechanisms of the action of laser radiation on biological tissues by means of changes in metabolism, leading to molecular, cellular and systemic changes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 55 Years 至 65 Years（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •stage I hypertensive patients
- •patients from 30 to 34.9 kg/m2 body mass index
- •medically stable patients
- •all participants have sufficient cognition enough to understand the requirements of the study
排除标准
- •history of malignant disease
- •history of progressive fatal disease
- •history of drug or alcohol abuse
- •blood donation within at least 30 days
- •pregnant, trying to be pregnant or breast feeding
- •cognitive impairment that will make it difficult to partake in the study
研究组 & 干预措施
low level laser hemotherapy
Watch laser acupuncture and nasal irradiation
干预措施: low level laser hemotherapy (Device)
control
all the participants in this group did not receive low level laser irradiation during the study period
结局指标
主要结局
changes of blood pressure
时间窗: 8 weeks
measuring blood pressure before and after each low level laser radiation
次要结局
- changes in blood viscosity(8 weeks)
- change in IL-17 level(45 days)
- change in functional capacity(70 days)
- change in CD 8 (cluster of differentiation 8) level(45 days)
- change in TC (total cholesterol) level(60 days)
- change in LDL (low density lipoprotien) level(60 days)
- change in TG (triglyceride) level(60 days)
- change in HDL (high density lipoprotien) level(60 days)
研究者
Ebtesam Nabil
lecturer assistance at Cairo University
Cairo University