EUCTR2009-016855-23-GB进行中（未招募）1 期
Targeting systemic inflammation to improve endothelial function in obesity - Inflammation, obesity and endothelial function
niversity of Leeds0 个研究点目标入组 50 人开始时间: 2010年7月19日最近更新:
适应症
相关药物
试验速览
- 阶段
- 1 期
- 状态
- 进行中（未招募）
- 发起方
- 入组人数
- 50
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional clinical trial of medicinal product
入排标准
- 性别
- All
入选标准
- •obesity (Body Mass Index 30 or greater)
- •not taking other medication (apart from oral contraceptives)
- •Are the trial subjects under 18? no
- •Number of subjects for this age range:
- •F.1.2 Adults (18-64 years) yes
- •F.1.2.1 Number of subjects for this age range
- •F.1.3 Elderly (>=65 years) no
- •F.1.3.1 Number of subjects for this age range
排除标准
- •hypertension
- •hyperlipidaemia
- •cardiovascular disease or history of cardiac arrythmias
- •chronic inflammatory disorders (e.g. rheumatoid arthritis, connective tissue disorders, gout, inflammatory bowel disease, chronic infections)
- •acute inflammatory illnesses (e.g. upper respiratory tract infections)
- •allergy to pentoxifylline or other methyl xanthine drugs or concomitant use of sildenafil, tadalafil, vardenafil or other phosphodiesterase 5 inhibitors
- •history of cerebral haemorrhage or retinal haemorrhage
- •pregnancy or breastfeeding
- •Impaired renal function
- •Hypotension (systolic blood pressure less than 90mmHg)
研究者
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