NCT00300508已完成3 期
A Randomized, Open, Comparative Multicentre Trial of 3 Years Anastrozole Treatment vs. 3 Years no Treatment in Postmenopausal Patients With Breast Cancer Who Have Completed 5 Years Adjuvant Hormone Therapy.
适应症
相关药物
试验速览
- 阶段
- 3 期
- 状态
- 已完成
- 发起方
- AstraZeneca
- 入组人数
- 856
- 试验地点
- 51
- 主要终点
- Recurrence-free and overall survival
研究概览
简要总结
The study assesses the effect of a further 3 years adjuvant treatment with anastrozole vs. an untreated control group after initial 5 years of adjuvant hormone-therapy.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- — 至 80 Years（Child, Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •No disease recurrence at time of randomization,
- •patients with breast cancer after surgery,
- •5 years (+/- 12 months) of prior endocrine therapy
排除标准
- •Premenopausal patients,
- •unknown or negative receptor status,
- •Secondary malignant tumor
结局指标
主要结局
Recurrence-free and overall survival
次要结局
- Secondary cancers
研究者
研究点 (51)
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