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eural and behavioral markers for the motivational negative symptoms of schizophrenia – a longitudinal approach - SyMoNe

Charité - Universitätsmedizin BerlinKlinik für Psychiatrie und Psychotherapie0 个研究点目标入组 175 人开始时间: 2017年4月5日最近更新: 2024年8月19日

适应症

试验速览

暂无简介。

•In order to be eligible to participate in this study, all participants must meet all of the following criteria:
•18-60 years old
•Written informed consent
•In patients the diagnostic criteria are:
•DSM-5 diagnosis of schizophrenia on the basis of the Structured Clinical Interview for DSM-5 (SCID-I)
•Clinical stability as judged by the treating psychiatrist and indicated by no change in medication in the two weeks prior to the initial assessment

•Any potential subject who meets any of the following criteria will be excluded from participation in this study:
•Any previous neurosurgery or neurological disorder, including epilepsy
•History of head injury resulting in unconsciousness lasting at least 1 hour
•Pregnancy or lactation
•Any contraindications for MRI such as ferromagnetic/non-MRI-compatible items or medical devices on or in the body (for example pacemaker, brain stimulator, clips, metal implants)
•sensorineural hearing loss of 30dB or more or history of tinnitus
•Incompetency to fully comprehend the purpose of the study or to make a rational decision whether or not to participate
•In patients additional exclusion criteria are:
•Benzodiazepine use of more than 1mg lorazepam equivalents per day
•Comorbid axis-I disorder

发起方

Charité - Universitätsmedizin BerlinKlinik für Psychiatrie und Psychotherapie