Clopidogrel for the prevention of late cardiac events in patients with asymptomatic perioperative acute coronary syndrome. - DECREASE VII

ijf en Leven0 个研究点开始时间: 2008年9月10日最近更新: 2012年3月19日

试验速览

暂无简介。

•Inclusion Criteria Men and women who are scheduled for major vascular surgery are eligible for the trial.Eligible patients include those above the age of 18 years and at least one of the following:
•1.abdominal aortic aneurysm repair
•2.aortic stenosis repair
•3.above knee femoropopliteal bypass surgery
•4.below knee femoropopliteal bypass surgery.
•And with postoperative asymptomatic troponin T release without ECG abnormalities.
•Are the trial subjects under 18? no
•Number of subjects for this age range:
•F.1.2 Adults (18-64 years) yes
•F.1.2.1 Number of subjects for this age range
•F.1.3 Elderly (>=65 years) yes
•F.1.3.1 Number of subjects for this age range

•Exclusion Criteria Potential subjects will be excluded with any of the following :
•1. Active bleeding
•2. Untreated left main disease
•3. Active cardiac condition such as unstable angina pectoris, active CHF, serious cardiac arrhythmias, symptomatic valvular disease, recent < 6 months.
•4. Preoperative positive troponin T
•5. Inability to take clopidogrel orally
•6. clear indication for long-term clopidogrel use
•7. previous allergy or intolerance to clopidogrel
•8. renal failure requiring dialysis
•9. significant liver disease (i.e. ALAT, ASAT >3x ULN)
•10. cancer with an expected life expectancy < 6 months
•11. anticipated non-adherence to clopidogrel
•12. excessive alcohol use
•13. pregnancy or planning to become pregnant
•14. failure to provide informed consent

发起方

ijf en Leven