A randomised prospective clinical trial for evaluation of clinical effectiveness of autogenous tooth graft in socket preservation which is a clinical,radiological and histological study.
试验速览
- 阶段
- 1 期
- 状态
- 尚未招募
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- 1.To assess the effectiveness of autogenous tooth graft in preserving the extracted alveolar socket , using radiological segmental CBCT evaluation of socket width and socket height and histological evaluation using punch biopsy after 6 months.
研究概览
简要总结
The aim of the study is to evaluate the clinical , radiological and histological effectiveness of autogenous tooth graft in preserving the extracted alveolar socket.The purpose of this study is to preserve the alveolar dimension of the extracted alveolar socket by using autogenous tooth graft which will aid in successful accomplishment of future rehabilitation.The objective of the study is to assess the effectiveness of autogenous tooth graft in preserving the extracted alveolar socket , using radiological segmental CBCT evaluation of socket width and socket height and histological evaluation using punch biopsy after 6 months and prepare the site for future prosthetic rehabilitation and implant placement .
Informed consent will be obtained.Extraction will be done under Local Anaesthesia using 2% Lignocaine and 1:80,000 Adrenaline.Preparation and sectioning of the teeth will be done.Grinding and Cleansing the particulate.Graft material will be obtained , placed in the socket and sutured.Radiographic evaluation: segmental Cone-beam computed tomography (CBCT). Radiographic assessment –Baseline -immediately ,postoperatively: 3month and 6month.Punch biopsy will be perfomed after 6 month.Histological analysis of new woven bone formation using hematoxylin and eosin stain will be done.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 盲法
- None
入排标准
- 年龄范围
- 20.00 Year(s) 至 50.00 Year(s)（—）
- 性别
- All
入选标准
- •Age between 20 and 50 years.
- •Systemically healthy patients.ASA 1,ASA 2 Patients who require tooth extraction due to localized periodontitis,trauma and tooth fracture.
- •Patient having a tooth indicated for extraction which could be used for autograft.
- •Patient who received instruction on the purpose of the clinical study and gave his /her consent.
排除标准
- •Systemic illness such as diabetes mellitus, cardiac diseases, immune-compromised , patients taking medications such as corticosteroids, calcium channel blocker or bisphosphonates which are known to interfere with the outcome.
- •Pregnant and lactating patients.
- •Grossly decayed and RCT treated teeth Alcoholics and Smokers.
- •Patients who demonstrate poor oral hygiene maintenance.
- •Patient who has received radiation therapy.
- •Patient who has acute infections.
结局指标
主要结局
1.To assess the effectiveness of autogenous tooth graft in preserving the extracted alveolar socket , using radiological segmental CBCT evaluation of socket width and socket height and histological evaluation using punch biopsy after 6 months.
时间窗: 6 months
次要结局
- To prepare the site for future prosthetic rehabilitation and implant placement(6 months)
研究者
Tanya Singh
Army college of dental sciences