跳至主要内容
临床试验/EUCTR2004-004893-96-GB
EUCTR2004-004893-96-GB进行中(未招募)1 期

Randomised double-blind trial of combination antibiotic therapy in rheumatoid arthritis

Hammersmith Hospitals NHS trust0 个研究点目标入组 50 人开始时间: 2005年2月15日最近更新:
适应症
相关药物

试验速览

阶段
1 期
状态
进行中(未招募)
发起方
入组人数
50

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional clinical trial of medicinal product

入排标准

性别
All

入选标准

  • Age 18 -30
  • Classical Rheumatoid Arthritis
  • Erosions on joint radiographs
  • Rheumatoid factor posiyive
  • Disease duration>6 months
  • Active disease 6 or more inflamed joints: ESR>20mm/hr or CRP>12 mg/ml
  • Failed on methotrexate> or= 7.5 mg/week
  • No anti-TNF therapy for at least three months
  • Are the trial subjects under 18? no
  • Number of subjects for this age range:
  • F.1.2 Adults (18-64 years) yes
  • F.1.2.1 Number of subjects for this age range
  • F.1.3 Elderly (>=65 years) yes
  • F.1.3.1 Number of subjects for this age range

排除标准

  • Severe disease
  • Chronic recurrent infection
  • Immunodeficiency
  • Inflammatory bowel disease
  • Other diarrhoeal states
  • Other major illnessess
  • History of adverse reactions to tetracycline, clindamycin or similar antibiotics
  • Pregnancy or lactation

研究者

发起方
Hammersmith Hospitals NHS trust

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