Blood Flow Restriction Training in Acute Geriatric Rehabilitation: A Randomized Controlled Trial on Its Effects and Safety in Hospitalized Older Adults.
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- 入组人数
- 60
- 试验地点
- 2
- 主要终点
- Muscle Strength
研究概览
简要总结
Background: Older adults have a reduced ability to build and maintain muscle mass due to age-related changes in the muscular system. The resulting sarcopenia can lead to a number of health problems and limitations, such as an increased risk of falling and reduced mobility, which can affect quality of life and increase the risk of disease. To increase muscle mass and strength, high-intensity resistance training with loads of 70 to 85% of the repetition maximum (1RM) is recommended. However, this type of training poses a major challenge in the rehabilitation sector, as there is also an increased risk of injury due to physical limitations in old age. According to current research, low-intensity occlusion training could therefore represent a safe and effective training alternative. The aim of this study is therefore to examine the feasibility and effects of blood flow restriction training (BFR) on general health in older adults in a rehabilitative setting.
详细描述
The study is a randomized controlled trial with a pre-post design. Participants will be recruited from the of St. Marien Hospital Geriatric Rehabilitation Center in Cologne, Germany. Patients will be randomized into 2 groups. The intervention group will receive BRF training on a stationary cycling ergometer five times a week over a period of two weeks, while the control group will receive sham-BFR training.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 65 Years 至 —（Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adults >65 years with a two week hospitalized acute rehabilitation after a fracture closed to the hip joint
排除标准
- •Sickle Cell Anemia
- •Iatrogenic changes of the vessels at the place of the tournqiuet application (e.g. Stents)
研究组 & 干预措施
Intervention Group
Blood-Flow-Restriction Training
干预措施: Stationary Bike + Blood-Flow-Restriction (Device)
Control Group
Sham-Blood-Flow-Restriction Training
干预措施: Stationary Bike + Sham-Blood-Flow-Restriction (Device)
结局指标
主要结局
Muscle Strength
时间窗: Pre-Rehabilitation to Post-Rehabilitation (after 2 weeks)
Isometric Maximal Strength Test of the Knee Extensors (in kg)
Timed Up and Go Test
时间窗: Pre-Rehabilitation to Post-Rehabilitation (after 2 Weeks)
The Timed Up and Go Test (TUG) is a widely used English-language assessment for measuring functional mobility and fall risk in older adults. It records the time required to stand up from a chair, walk three meters, turn around, and sit down again.
次要结局
未报告次要终点
研究者
Alexander Franz
Principal Investigator
University Hospital, Bonn