A Prospective Observational Study of the Perfusion Index an a Predictor of Return of Spontaneus Circulation in Out of Hospital Cardiac Arrest
试验速览
- 阶段
- 不适用
- 发起方
- 入组人数
- 90
- 试验地点
- 1
- 主要终点
- Return of Spontaneous Circulation - Perfusion index - absolute values
研究概览
简要总结
The purpose of this pilot feasibility study is to evaluate the ability of the Perfusion Index to predict the return to spontaneous circulation of the out-of-hospital cardiac arrest patient during cardiopulmonary resuscitation.
The performance of the perfusion index will also be compared to the current gold standard, end-tidal CO2 (EtCO2).
详细描述
The aim of this observational research is to measure the predictive performance the perfusion index to predict a return of a spontaneous circulation (ROSC) during cardiopulmonary resuscitation (CPR).
The research focuses on patients in out-of-hospital cardiac arrest (OHCA) and in-hospital cardiac arrest (IHCA) treated by the mobile intensive care unit of Saint Pierre University Hospital.
The study will be a pilot observational study during cardiac arrest. During the study period a non-invasive sensor will be connected to the patient's finger to measure continously and non-invasively the perfusion index. This non-invasive measurement is done by means of an infrared light which has no known risks for the health of the patient and which is usually used for the measurement of arterial oxygen saturation (SatO2). No intervention is planned as no decision will be taken on treatment based on the collected values of perfusion index during the arrest and post-arrest care of the participants.
The study will therefore be conducted during conventional advanced life support procedures without rescuers having access to the ongoing measurements.
The study will end when the participant returns to spontaneous circulation (RACS) or when patients is admitted to the emergency ward, whichever comes first in a time frame of maximum two hours.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 12 Years 至 99 Years（Child, Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Out of hospital cardiac arrest with an indication to initiate chest compressions
- •In hospital cardiac arrest with an indication to initiate chest compressions
排除标准
- •Pregnant patients
- •Prisoners
结局指标
主要结局
Return of Spontaneous Circulation - Perfusion index - absolute values
时间窗: From study inclusion until hospital admission or date of death from any cause, whichever came first, assessed up to 2 hours after inclusion
Receiver operating characteristic curve of the perfusion index to predict return of spontaneous circulation. Area under the curve of the receiver operating curve will be measured and reported for absolute values.
Return of Spontaneous Circulation - Perfusion index - trend values
时间窗: From study inclusion until hospital admission or date of death from any cause, whichever came first, assessed up to 2 hours after inclusion
Receiver operating characteristic curve of the perfusion index to predict return of spontaneous circulation. Area under the curve of the receiver operating curve will be measured and reported for trend values of the pulsatility index.
次要结局
- Return of Spontaneous Circulation - EtCO2 - Perfusion index(From study inclusion until hospital admission or date of death from any cause, whichever came first, assessed up to 2 hours after inclusion)