The Effect of Osteopathic Manual Therapy on the Vascular Supply to the Lower Extremity in Individuals With Knee Osteoarthritis, a Randomized Trial
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 30
- 试验地点
- 2
- 主要终点
- Resistive Index (RI)
研究概览
简要总结
The purpose of this study is to determine if the use of osteopathic manual therapy can influence the vascular supply to the knee, knee range of motion, balance and knee pain, in a group of subjects with knee osteoarthritis. It is also the objective of this study to determine if there is a difference between the osteopathic evaluation and the combination of an osteopathic evaluation and treatment.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Treatment
- 盲法
- Double (Participant, Outcomes Assessor)
入排标准
- 年龄范围
- 50 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Radiographic-confirmed knee osteoarthritis
排除标准
- •Subjects who are unable to ambulate independently (without an aid) and safely the distance of a city block
- •Subjects who have an uncontrolled medical condition (e.g. heart (angina) or respiratory condition (asthma))
- •Subjects who have a neurological condition (e.g. Parkinson's, Multiple Sclerosis)
- •Subjects who have both knees affected by osteoarthritis and have had previous surgery to both knees
- •Subjects who have knee OA in only one knee and that knee has had previous knee surgery
- •Subjects who have previous vascular surgery to either leg
结局指标
主要结局
Resistive Index (RI)
时间窗: Participants attended one visit; The outcome measure (RI) was before and after an osteopathic session on the same day; The data collection of the 30 subjects took place between Jan to March 2010; each subject had outcomes measured on one day
Ultrasonographic examination provides a non-invasive method to assess blood flow dynamics. The resistive index (RI), calculated from arterial blood flow velocities, reflects vascular resistance. The RI was calculated by dividing the peak systolic velocity (PSV) minus the end-diastolic velocity by the peak systolic velocity, and is cited frequently in the literature for measuring hemodynamics of peripheral vessels.
次要结局
- The Knee Flexion Active Range of Motion, Balance and Pain (VAS)(Jan 2010 to March 2010)
研究者
Wendy Jardine
Physiotherapist osteopath
Nova Scotia Health Authority