The Effect of Intravitreal Aflibercept for Neovascular membrane, Pigment Epithelial Detachment and/or Subretinal Fluid Secondary to Type 1 Choroidal Neovascularization: Quantitative analysis based on OCT and OCT Angiography

Kyung Hee University Hospital0 个研究点目标入组 40 人开始时间: 待定最近更新: 2022年6月27日

适应症

试验速览

暂无简介。

•1. Active choroidal neovascularization confirmed by optical coherence tomography angiography or fluorescein angiography and indocyanine green angiography
•- When the subretinal fluid accompanied by irregular elevation of the retinal pigment epithelium is confirmed by optical coherence tomography
•- In cases where choroidal neovascularization is observed in optical coherence tomography angiography or fluorescein angiography and indocyanine green angiography
•2. Male or female patients over 50 years of age who have signed the informed consent form
•3. In the absence of active ocular or systemic disease
•4. Patients who understand the process of this clinical trial, are cooperative, and are judged to be able to participate by the end of the clinical trial

•1. Pregnant or lactating women
•2. Patients participating in other clinical trials
•3. If patient have received anti-vascular endothelial growth factor treatment within the last 90 days
•4. If patient have received photodynamic therapy 3 times or more or within the last 90 days
•5. Clinically prominent diabetic retinopathy or diabetic macular edema
•6. Clinically significant scar or atrophy of the fovea
•7. Active Intraocular Inflammation or Infection
•8. In case of hypersensitivity to Afilbercept and other ingredients in Eylea
•9. History of intravitreal triamcinolone injection treatment within the last 3 months
•10. History of intravitreal dexamethasone injection treatment within the last 6 months
•11. History of use of inhaled or sprayed or dermal steroids for more than 30 consecutive days within the last 3 months
•12. History of eye surgery, including vitrectomy, glaucoma surgery, and scleral buckling within the last 3 months (Excluding simple cataract surgery and vision correction surgery)
•13. Diagnosed with retinal vascular disease other than age-related macular degeneration
•14. Cerebrovascular disease, myocardial infarction diagnosed within the one year

发起方

Kyung Hee University Hospital