跳至主要内容
临床试验/NCT00625105
NCT00625105Unknown不适用

Using Heart Rate Variability Biofeedback to Improve Attention and Memory in PTSD+ Combat Veterans

William Jennings Bryan Dorn VA Medical Center2 个研究点 分布在 1 个国家目标入组 30 人开始时间: 2011年1月1日最近更新:
适应症

试验速览

阶段
不适用
发起方
入组人数
30
试验地点
2
主要终点
Heart rate variability

研究概览

简要总结

This study will test the effectiveness of Heart Rate Variability (HRV) Biofeedback as a therapeutic tool in the reduction of everyday memory problems routinely experienced by combat veterans with Posttraumatic Stress Disorder (PTSD). The study is innovative in three ways: (1) through its investigation of the clinical use of a novel PTSD treatment technology, (2) by focusing on the understudied aspect of the daily functioning of PTSD veterans, and, (3) by investigating a heretofore untested application of biofeedback for PTSD induced deficits in attention (ATTN) and immediate memory (IM). Though HRV Biofeedback has proven successful for several applications in the general population, the idea that deficits in ATTN/IM in combat veterans with PTSD can be remedied by normalization of HRV has not yet been tested empirically. HRV is functionally incorporated into attentional processes, essentially operating as an index of autonomic flexibility and the ability to self-regulate in response to stimulation from the environment. Low HRV occurs in patients with PTSD, General Anxiety Disorder, and Coronary Artery Disease, and is correlated with negative affect and hostility. HRV Biofeedback training has been shown to be effective in increasing HRV in these groups of patients, as well as improving psychological well-being and physiological function in patients with Depression, Fibromyalgia, and Cardiovascular Disease. Therefore, the interrelationship between HRV and ATTN/IM problems in PTSD+ Combat veterans warrants further investigation. If HRV Biofeedback significantly improves ATTN/IM in these subjects, then it can be offered to VA clinicians treating combat PTSD as an effective new treatment tool.

研究设计

研究类型
Interventional
分配方式
Randomized
干预模型
Factorial
主要目的
Treatment
盲法
Single (Outcomes Assessor)

入排标准

年龄范围
20 Years 至 40 Years(Adult)
性别
All
接受健康志愿者

入选标准

  • OIF/OEF veterans with PTSD

排除标准

  • Neurologic disorder
  • Active substance abuse

结局指标

主要结局

Heart rate variability

时间窗: completion

Attention and immediate memory

时间窗: completion

次要结局

未报告次要终点

研究者

发起方
William Jennings Bryan Dorn VA Medical Center
申办方类型
Fed
责任方
Principal Investigator
主要研究者

J.P. Ginsberg, Ph.D.

Principal Investigator

William Jennings Bryan Dorn VA Medical Center

研究点 (2)

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